Description General description Dapsone is an antibacterial drug, belongs to a class of compounds known as sulfones. It acts by inhibiting the synthesis of dihydrofolic acid through competition with para-aminobenzoate for the active site of dihydropteroate synthetase, thereby inhibiting the growth of microorganisms that are dependent on endogenous folic acid synthesis. It is used in primary treatment of dermatitis herpetiformis and in combination with other drugs to treat leprosy.[1] Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Application Dapsone may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by chromatography.[2][3] These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. Analysis Note These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. Other Notes This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. Footnote To see an example of a Certificate of Analysis for this material enter LRAA3012 in the slot below. This is an example certificate only and may not be the lot that you receive.