Description_x000D_ General description_x000D_ Dipyridamole prevents cellular uptake of adenosine. It functions as an equilibrative nucleoside transporter 1 (ENT1) inhibitor._x000D_ Application_x000D_ Dipyridamole has been used:_x000D_ • to perform in vitro growth inhibition assay(40)_x000D_ • to determine its ability to prevent uterine myometrial contractions(41)_x000D_ • to determine its effects on nicotinamide adenine dinucleotide (NAD+)-induced increase in intracellular adenosine triphosphate (ATP) levels(42)_x000D_ • to prevent nicotinamide riboside (NR)-induced axonal protection(43)_x000D_ Packaging_x000D_ 1, 5, 10, 25 g in glass bottle_x000D_ Biochem/physiol Actions_x000D_ Selective inhibitor of phosphodiesterase V (PDE 5); potent coronary vasodilator drug; adenosine transport inhibitor; inhibitor of platelet aggregation._x000D_ Features and Benefits_x000D_ This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm._x000D_ This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more._x000D_ This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here._x000D_ This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here._x000D_ Legal Information_x000D_ LOPAC is a registered trademark of Sigma-Aldrich Co. LLC