Description_x000D_ General description_x000D_ Alkaline hydrolysis of mevalonolactone gives mevalonate. Mevalonate is a precursor of farnesyl and geranylgeranyl pyrophosphates. These pyrophosphates are required for protein prenylation._x000D_ Application_x000D_ (±)-Mevalonolactone is used to:_x000D_ • study the effect of statin on the prenylation of Ras and Rho GTPases_x000D_ • analyse the isoprenoid biosynthesis pathways in Listeria monocytogenes_x000D_ • study the the effects of statins on proliferation and migration of HUVECs (HGF-induced human umbilical vein endothelial cells)_x000D_ Packaging_x000D_ 1, 5, 10 g in glass bottle_x000D_ Other Notes_x000D_ Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. M4667.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin._x000D_ May also be liquid!