Description_x000D_ Application_x000D_ • In yeast cells, doxycycline has been used in doxycycline-inducible system for overexpression of methyltransferase Hmt1 (hnRNP methyltransferase 1)._x000D_ • It has been used in the doxycycline-inducible IFITM (interferon-induced transmembrane) cell lines._x000D_ • It has also been used as an antimicrobial agent._x000D_ Biochem/physiol Actions_x000D_ Doxycycline is a semisynthetic tetracycline that is active against bacteria, mycoplasma and protozoan parasites. It inhibits the bacterial protein synthesis by inhibiting the interaction of aminoacyl-tRNA and the bacterial ribosome._x000D_ Other Notes_x000D_ Keep container tightly closed in a dry and well-ventilated place.