Description General description A cell-permeable cationic surfactant that reversibly inhibits dynamin GTPase activity (IC50 = 3.15 µM) by targeting the PH domain and interfering with phospholipid binding. Shown to block dynamin I-dependent SVE (synaptic vesicle endocytosis) in rat brain synaptosomes and dynamin II-dependent RME (receptor-mediated endocytosis) in non-neuronal HeLa, A431, and COS-7 cells. Inhibition is competitive with respect to PS and noncompetitive with respect to GTP. Packaging 500 mg in Glass bottle Packaged under inert gas Warning Toxicity: Corrosive (L) Reconstitution Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Other Notes Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges. Quan, A., et al. 2007. Mol. Pharmacol.72, 1425. Hill, T.A., et al. 2004. Bioorg. Med. Chem. Lett.14, 3275.; Description