Description_x000D_ Biochem/physiol Actions_x000D_ The SML0168 ligand was shown to antagonize the activity of the histamine agonist, histamine, in two separate recombinant CHO cell lines expressing either the human H2 or H3-receptor and a cyclic-AMP responsive secreted placental alkaline phosphatase (SPAP) reporter gene._x000D_ Features and Benefits_x000D_ This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here._x000D_ Reconstitution_x000D_ Dissolve 0.2 mg in 23.5 ul of DMSO to give a 10mM stock solution. Once reconstituted into DMSO the product, must be stored, preferably in smaller aliquots, at -20°C.