Description_x000D_ Application_x000D_ Fluvastatin sodium hydrate has been used:_x000D_ • to examine its effect on β -glucan-induced training on immunity_x000D_ • to investigate the effect of statins on the number of uncoupling protein 1 (UCP1)+ cells_x000D_ • to determine its effect on insulin degrading enzyme (IDE) secretion from astrocytes_x000D_ • to treat and study its effect on human umbilical vein endothelial cells (HUVECs) in vitro_x000D_ Fluvastatin sodium hydrate has been used:_x000D_ • to test its anti-hepatitis C virus (HCV) activity_x000D_ • as a cholesterol inhibitor_x000D_ • to study its effects on β-glucan-induced monocyte immune training_x000D_ Packaging_x000D_ 10, 50 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ Fluvastatin has antifungal activity._x000D_ Fluvastatin is a competitive inhibitor of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Fluvastatin is antilipemic and is used to reduce plasma cholesterol levels and prevent cardiovascular disease._x000D_ Features and Benefits_x000D_ This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.