Description_x000D_ General description_x000D_ Fucoidan is a fucose-rich, sulfated polysaccharide isolated from several species of brown seaweed._x000D_ Application_x000D_ Fucoidan from Fucus vesiculosus may be used as a biological response modifier and as a potential therapeutic agent with a wide range of biological activities. It may be used to study its pharmacokinetics, safety, efficacy and methods of delivery as a potential anticancer, anti-immune and anti-inflammatory agent. Fucoidan may be used to assess its potential and formulations for tissue engineering applications._x000D_ Packaging_x000D_ 1 g in poly bottle_x000D_ 500 mg in poly bottle_x000D_ Biochem/physiol Actions_x000D_ Studies of fucoidan have found it to have a broad variety of biological activities including antitumor and antiangogenic activities, immunomodulatory, anti-inflammatory, anticoagulant, antithrombotic, and antioxidant activities. Fucoidan induces macrophage activation with subsequently activates mitogen activated protein kinases (MAPKs) and results in natural killer cell proliferation. Fucoidan acts as a nonselective selectin blocker and has been shown to induce apoptosis and suppress angiogenesis._x000D_ Preparation Note_x000D_ Prepared by a modification of the method of Black, W.A.P., et al., J. Sci. Food Agri., 3, 122 (1952).