Description General description A fluorogenic substrate for furin (kcat/Km ~2 X 104 M-1 s-1), a mammalian homolog of the yeast Kex2 endoprotease. Also serves as a substrate for related protein, prohormone convertase 2 (PC2) (kcat/Km ~6 X 103 M-1 s-1). Excitation max: ~360-380 nm; emission max: ~430-460 nm). A fluorogenic substrate for furin, a mammalian homolog of the yeast Kex2 endoprotease (kcat/Km ~ 2 x 104 s-1M-1). Packaging 5 mg in Plastic ampoule Biochem/physiol Actions Cell permeable: no Primary Target Fluorogenic substrate for furin Product does not compete with ATP. Reversible: no kcat/Km ~ 2 x 104 s-1M-1 for furin Warning Toxicity: Standard Handling (A) Sequence Pyr-Arg-Thr-Lys-Arg-AMC Physical form Supplied as a trifluoroacetate salt. Reconstitution Following reconstitution, aliquot and freeze (-20°). Stock solutions are stable for up to 3 months at -20°C. Other Notes Lamango, N.S., et al. 1996. Arch. Biochem. Biophys.330, 238. Hatsuzawa, K., et al. 1992. J. Biol. Chem. 267, 16094.; Description