Description General description A cell-permeable caspase activator and an apoptosis inducer that was originally isolated from gamboge resin for its antimicrobial properties. Shown to inhibit the growth of HeLa and HEL cells minimal inhibitory concentrations (MIC = 12.5 µg/ml). A cell-permeable, anti-microbial xanthone orignally isolated from the gamboge resin of Garcinia hanburyi. Acts as a caspase activator and apoptosis inducer. Shown to inhibit the growth of HeLa and HEL cells (MIC = 12.5 µg/ml). Reported to block telomerase activity in SMMC-7721 cells. Shown to induce tyrosine kinase phosphatase SHP-1 and suppress Stat3 activation. Packaging 25 mg in Alu drum Biochem/physiol Actions Cell permeable: yes MIC = 12.5 µg/ml in inhibiting the growth of HeLa and HEL cells Primary Target Caspase activator and an apoptosis inducer Product does not compete with ATP. Reversible: no Packaging Packaged under inert gas Warning Toxicity: Toxic & Carcinogenic / Teratogenic (G) Other Notes Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges. Prasad, S., et al. 2011. Cancer Prev. Res.4, 1084. Guo, Q.L., et al. 2004. Acta Pharmacol. Sin.25, 769. Asano, J., et al. 1996. Phytochemistry41, 815.; Description