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GELDANAMYCIN FROM STREPTOMYCES HYGROSCOP
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GELDANAMYCIN FROM STREPTOMYCES HYGROSCOP
Кол-во:
Цена по запросу
Товар оформляется под заказ
Печать
GELDANAMYCIN FROM STREPTOMYCES HYGROSCOP
Кол-во:
Цена по запросу
Товар оформляется под заказ
Description_x000D_
General description_x000D_
Chemical structure: benzenoid_x000D_
Packaging_x000D_
1 mg in glass bottle_x000D_
Biochem/physiol Actions_x000D_
Geldanamycin is a potent antitumor antibiotic active at nanomolar concentration against 60 cell lines._x000D_
Geldanamycin binds specifically to the heat shock protein Hsp90 and to its endoplasmic reticulum homologue GP96, and thus interferes with conformational maturation of proteins and the cellular stress response. In addition, Geldanamycin is a potent inhibitor of the nuclear hormone receptor family._x000D_
Features and Benefits_x000D_
This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm._x000D_
This compound is featured on the Met page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Related Categories
Antibiotics, Antibiotics A to Z, Antibiotics G-M, Antibiotics by Application, Antibiotics by Mechanism of Action, Antineoplastic and Immunosuppressive Antibiotics, Antitumor Agents, Benzenoids, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Cancer Research, Cell Biology, Cell Signaling and Neuroscience, Cell Stress, Chaperonins and Heat Shock Proteins, Chemical Structure Class, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, G, HSP-90 Inhibitors, Heat Shock and Related Proteins, Inhibits an Enzyme, Kinase/Phosphatase Biology, Molecular Biology, Nitric Oxide and Cell Stress, P to Q, Phosphorylation Analysis, Post-Translational Modification, Protein Kinase Inhibitors, Protein kinase erbB2,2, Protein kinase v-src, Protein kinase, tyrosine, EGF receptor, Proteomics, Receptor Tyrosine Kinase Biology, Receptor Tyrosine Kinase Inhibitors, Small Molecules for Stem Cell Biology, Stem Cell Biology, Tyrosine Kinase (TK), Tyrosine Kinase InhibitorsMore... Quality Level
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