Description_x000D_ Application_x000D_ Gelsolin from bovine plasma was used in actin assembly assays._x000D_ Packaging_x000D_ 0.2, 0.5 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ Gelsolin is an actin-binding protein that regulates the assembly and disassembly of actin filaments._x000D_ Gelsolin is an actin-severing protein found in mammalian cells and blood plasma. Exhibits tumor suppressor activity in several cancer cell lines and in nude mice._x000D_ Packaging_x000D_ Package size based on protein content_x000D_ Unit Definition_x000D_ One unit will reduce viscosity difference between actin solution and buffer by 50% in a 1 mL mixture containing 1-2mg F-actin, 0.15 M KCl, 20 mM Tris, pH 7.6, 0.2 mM CaCl2, 0.2 mM ATP, and 1 mM DTT at 28 °C._x000D_ Physical form_x000D_ Lyophilized powder containing NaCl, Tris buffer salt, and EGTA