Description_x000D_ General description_x000D_ Chemical structure: aminoglycoside_x000D_ Application_x000D_ Gentamicin solution has been used to study its dose-related antipruritic effects on serotonin (5-HT)-induced scratching model. It has also been used in electrophysiological analysis._x000D_ Biochem/physiol Actions_x000D_ Mode of Action: Gentamicin inhibits protein synthesis by binding to the 30S subunit of the ribosome._x000D_ Antimicrobial spectrum: Includes Gram-negative and Gram-positive bacteria, including strains resistant to tetracycline, chloramphenicol, kanamycin and colistin, particularly strains of Pseudomonas, Proteus, Staphylococcus and Streptococcus._x000D_ Components_x000D_ Gentamicin is an aminoglycoside complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is used as the sulfate salt. There are three components, each consisting of five basic nitrogens and requiresing five equivalents of sulfuric acid per mole of gentamicin base._x000D_ Caution_x000D_ The product is stable at 37° for 5 days and is stored at 2-8°C._x000D_ Legal Information_x000D_ Hybri-Max is a trademark of Sigma-Aldrich Co. LLC