Description_x000D_ General description_x000D_ Glucose 6-phosphate dehydrogenase (G-6-P-DH) is a key regulatory enzyme in the first step of the pentose phosphate pathway. G-6-P-DH is a glycoprotein with a molecular mass of 128 kDa (gel filtration)._x000D_ Application_x000D_ Glucose-6-phosphate dehydrogenase is used to test ketose reductase activity in developing maize endosperm._x000D_ Biochem/physiol Actions_x000D_ Glucose-6-phosphate dehydrogenase catalyzes the conversion of glucose-6-phosphate to 6-phosphogluconolacetone as the first step in the pentose phosphate pathway._x000D_ Unit Definition_x000D_ One unit will oxidize 1.0 μmole of D-glucose 6-phosphate to 6-phospho-D-gluconate per min in the presence of NAD at pH 7.8 at 30 °C._x000D_ Physical form_x000D_ Suspension in 3.2 M (NH4)2SO4 containing 50 mM Tris and 1 mM MgCl2, pH 7.5