Description_x000D_ Biochem/physiol Actions_x000D_ Glutamic-pyruvic transaminase (GPT) is located in most cells in the body, but is found in highest concentrations in the liver. It is used as a marker of liver disease due to the release of GPT into the blood following liver cell necrosis._x000D_ Unit Definition_x000D_ One unit will convert 1.0 μmole of α-ketoglutarate to L-glutamate per min at pH 7.6 at 37 °C in the presence of L-alanine._x000D_ Physical form_x000D_ Suspension in 1.8 M (NH4)2SO4 solution, pH 6.0_x000D_ Analysis Note_x000D_ Protein determined by biuret.