Description_x000D_ General description_x000D_ The antibody neutralizes the biological activity of recombinant human GDNF._x000D_ Immunogen_x000D_ recombinant human GDNF expressed in Escherichia coli._x000D_ Physical form_x000D_ Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline_x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ Glial cell-derived neurotrophic factor is a potent neurotrophic factor that is important for the maintenance, regeneration and survival of specific neuronal cells including autonomic neurons, motoneurons, noradrenergic and seotonergic neurons. Additionally, it promotes the invasion and metastatic behavior of certain types of cancers by activating ERK, p38, JNK and AP-1 mediated cell signaling._x000D_ Preparation Note_x000D_ Purified using protein G.