Description_x000D_ General description_x000D_ Interleukin-2 (IL-2) is a cytokine produced by activated T cells in response to antigen stimulation. IL-2 is important for proliferation of lymphocytes, natural killer cells and macrophages and in the differentiation of CD4+ cells into Th1 and Th2 effector cells. The effects of IL-2 are mediated by the signalling activated by its binding to IL-2 receptor (IL-2 R). IL-2 activates key signalling pathways such as MAPK, JAK/STAT as well as PI3K/Akt. Activation of these pathways modulates production of inflammatory cytokines, survival and progression through cell cycle_x000D_ Monoclonal Anti-Interleukin-2 recognizes human Interleukin-2. It also neutralizes recombinant, mouse IL-2, but requires 30-50 times the antibody concentration required to neutralize human IL-2._x000D_ Specificity_x000D_ The antibody neutralizes the biological activity of recombinant human IL-2._x000D_ Immunogen_x000D_ recombinant human interleukin-2 expressed in Escherichia coli._x000D_ Application_x000D_ Anti-interleukin-2 antibody is suitable for IL-2 neutralization assays._x000D_ Physical form_x000D_ Lyophilized from a 0.2 μm filtered solution of phosphate buffered saline containing carbohydrates._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Preparation Note_x000D_ Purified using protein G.