Description_x000D_ General description_x000D_ IgG subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids._x000D_ Immunogen_x000D_ Mouse IgG, Fc fragment_x000D_ Application_x000D_ Anti-Mouse IgG (Fc specific) antibody has been used in:_x000D_ • enzyme linked immunosorbent assay (ELISA)_x000D_ • Ouchterlony double diffusion_x000D_ • anti-drug antibody immunoassay_x000D_ • immunoelectrophoresis_x000D_ Physical form_x000D_ Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases . Mouse IgGs have four distinct isotypes, namely, IgG1, IgG2a, IgG2b, and IgG3. IgG1 regulates complement fixation in mice_x000D_ Other Notes_x000D_ Antibody adsorbed with human IgG and rat serum proteins_x000D_ Preparation Note_x000D_ Adsorbed to reduce background with human or rat samples.