Description_x000D_ General description_x000D_ Macrophage Inflammatory Protein-1-β is a member of the chemokine family and is produced in macrophages when stimulated by bacterial endotoxins. Anti-macrophage inflammatory protein-1β antibody can be used in immunoblotting. Goat anti-macrophage inflammatory protein-1β antibody reacts specifically with recombinant mouse MIP-1 β but does not react with recombinant human MIP-1 β or recombinant mouse or human MIP-1α._x000D_ Macrophage inflammatory protein-1 β (CCL4) belongs to a family of MIP-1 chemotactic cytokines (CC). The other members are CCL3 (MIP-1α), CCL9/10 (MIP-1δ) and CCL15 (MIP-1γ). The members of MIP-1 family have the ability to self-associate and form aggregates of high molecular weight. The self- aggregation is a reversible process and occurs in T cells, B cells and macrophages in response to inflammatory factors and bacterial endotoxins. This response results in inflammation and platelet degranulation_x000D_ Anti-Macrophage Inflammatory Protein-1β antibody is specific for mouse MIP-1 β. It shows less than 2% cross reactivity with recombinant mouse MIP-1α, recombinant human MIP-1α and MIP-1β._x000D_ Immunogen_x000D_ recombinant mouse MIP-1β expressed in E. coli._x000D_ Application_x000D_ Anti-Macrophage Inflammatory Protein-1β antibody may be for immunoblotting at a working concentration of 1.0 μg/ml. The antibody is suitable for neutralization reactions._x000D_ Physical form_x000D_ Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline, containing 5% trehalose_x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Preparation Note_x000D_ Purified using protein G.