Description_x000D_ General description_x000D_ GSTM1 (glutathione S-transferase μ 1) belongs to the superfamily of glutathione-S-transferases. It belongs to the μ class of soluble GSTs. GSTM1 is strongly expressed in the kidneys._x000D_ Biochem/physiol Actions_x000D_ Members of GST (glutathione S-transferase) superfamily are responsible for the metabolism of various reactive oxygen species and xenobiotics. GSTM1 (GST μ 1) plays a significant role in vascular homeostasis. Humans with null allele, GSTM1(0), are at increased risks for colon and lung cancers, hypertension, and atherosclerosis, and have higher DNA changes in atherosclerotic lesions of the abdominal aorta._x000D_ Physical form_x000D_ 1 mg/mL solution in PBS (pH 7.4) containing 5 mM Glutathione_x000D_ Preparation Note_x000D_ Centrifuge the vial prior to opening._x000D_ Other Notes_x000D_ MPMILGYWNV RGLTHPIRML LEYTDSSYDE KRYTMGDAPD FDRSQWLNEK FKLGLDFPNL PYLIDGSHKI TQSNAILRYL ARKHHLDGET EEERIRADIV ENQVMDTRMQ LIMLCYNPDF EKQKPEFLKT IPEKMKLYSE FLGKRPWFAG DKVTYVDFLA YDILDQYRMF EPKCLDAFPN LRDFLARFEG LKKISAYMKS SRYIATPIFS KMAHWSNK