Description_x000D_ Application_x000D_ Hck is a protein-tyrosine kinase that is expressed in hemopoietic cells. It is used in leukemia research ._x000D_ Biochem/physiol Actions_x000D_ Hck is a member of the Src tyrosine kinase family. Hck has been shown to associate with and be activated by Bcr-Abl, which is a protein-tyrosine kinase that is expressed in chronic myelogenous leukemia ._x000D_ Unit Definition_x000D_ One unit will phosphorylate 1.0 picomole of Tyr15 of the peptide substrate pcdc2 6-20 per minute at 30 °C at pH 7.4._x000D_ Physical form_x000D_ Supplied as a solution in 50 mM Tris HCl, pH 7.4, 1 mM EDTA and 1 mM DTT