Description_x000D_ General description_x000D_ Hemoglobin is the major component of red blood cells, and is responsible for their red color. Its normal concentration in erythrocytes is 34%. Hemoglobin is the most important respiratory protein of vertebrates by virtue of its ability to transport oxygen from the lungs to body tissues, and to facilitate the return transport of carbon dioxide._x000D_ Application_x000D_ Hemoglobin A0, ferrous stabilized human has been used:_x000D_ • as the non-fluorescent absorber in the preparation of tissue-mimicking phantoms_x000D_ • to see how coronary intraplaque hemorrhage evokes a novel atheroprotective macrophage phenotype_x000D_ • to study the interference of hemoglobin (Hb) A0, HbA2, and HbS in the assay of HbF_x000D_ Hemoglobin A0 was used to see how coronary intraplaque hemorrhage evokes a novel atheroprotective macrophage phenotype. It was used in the determination of fetal hemoglobin by time-resolved immunofluorometric assay._x000D_ Biochem/physiol Actions_x000D_ Variation in the haemoglobin (Hb) encoding genes results in haemoglobinopathies such as thalassaemia and atypical structural variants like Hb Lepore and HbE._x000D_ Packaging_x000D_ Package size indicates the amount of hemoglobin as determined by the procedure of Drabkin, D.L., J. Biol. Chem., 164, 703 (1946)._x000D_ Reconstitution_x000D_ When reconstituted with buffer, gives >85% ferrous hemoglobin.