Description_x000D_ Application_x000D_ Heparan sulfate sodium salt from bovine kidney has been used:_x000D_ • to investigate its effect on proliferation of B cells_x000D_ • to monitor its role on eye development in E5 embryonic cells_x000D_ • to study its binding with exosome fibronectin in human trabecular meshwork cells using dot blot_x000D_ Packaging_x000D_ 1, 5, 10 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ Heparan sulphate (HS), a ubiquitous glycosaminoglycan, is a polymer of D-glucuronic acid or L-iduronic acid and D-glucosamine (GlcA) sugars. It is synthesized in the cis-Golgi as heparan. In Golgi, final heparan sulphate is synthesized in by the action of enzymes N- and O-HS-sulphotransferases and HS epimerase. The mature HS has 50 to 200 disaccharide units. It is part of the extracellular matrix (ECM) and plays a key role in the oncogenic pathway. Deregulation of heparin sulfate metabolism is implicated in cancer progression. HS is associated with the onset of infectious diseases and inflammatory conditions. HS interaction with Aβ fibrils contributes to the pathophysiology of Alzheimer′s disease._x000D_ Constituent of membrane-associated proteoglycans suggested to contribute to cell-cell adhesion