Description General description Hexestrol is a synthetic nonsteroidal estrogen, which can be used in human medicine as well as a growth promoter in cattle. Application Hexestrol may be used as a reference standard for the determination of the analyte in biological samples using immunoaffinity extraction and gas chromatography-negative-ion chemical ionization mass spectrometry. Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. Packaging 1, 5 g in poly bottle Biochem/physiol Actions The carcinogen hexestrol is a nonsteroidal synthetic estrogen. Metabolic activation of hexestrol to its quinone, which reacts with DNA to form analogous depurinating adducts, may be a primary critical event leading to oncogenic mutations and cancer initiation. Linkage Reduced analogue of diethylstilbestrol.