Description_x000D_ General description_x000D_ This ELISA antibody pair detects Human Ghrelin (GHRL)_x000D_ Application_x000D_ For research use only. Not for use in diagnostic procedures._x000D_ Please refer to the attached Protocolfor details._x000D_ Biochem/physiol Actions_x000D_ The peptide ghrelin, one of the cleavage products of prepropeptide produced from the GHRL (growth hormone-releasing peptide) gene, functions in stimulating food intake and controlling energy balance. It has potent stimulating effects on the secretion of growth hormone. GHRL serves as an endogenous ligand for the growth hormone secretagogue receptor 1α (GHSR 1α). The protein regulates body weight on long-term and appetite on short-term. Preadipocyte differentiation stimulated by ghrelin is found to increase BMI and negatively regulate the anorexigenic effect of leptin. Polymorphism in the GHRL gene is linked to variations in blood pressure, high-density lipoproteins, low-density lipoproteins, serum cholesterol, blood glucose and metabolic syndrome._x000D_ Other Notes_x000D_ A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.