Description_x000D_ General description_x000D_ The IL36G ELISA kit provides for the Quantitative measurement of IL-36 gamma in Cell Culture Supernatants, Plasma and Serum._x000D_ Interleukin-36 gamma (IL36G), also known as IL-1F9, is a member of interleukin (IL)-1-like proinflammatory cytokine family. It is encoded by the gene mapped to human chromosome 2q12-q21. IL36G is abundantly expressed in epithelial tissues and numerous myeloid-derived cell types._x000D_ Application_x000D_ For research use only. Not for use in diagnostic procedures._x000D_ Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)_x000D_ Biochem/physiol Actions_x000D_ Members of interleukin (IL)-1 family of cytokines play a vital role in regulating immune responses to infectious challenges and sterile insults. IL-36 is implicated in mucosal immunity, such as lung anti-bacterial responses. Interleukin-36 γ (IL36G) participates in inflammation response and differentiation. Overexpression of IL36G has been observed in psoriasis patients. Thus, down regulation IL36G can be considered as an effective method to treat psoriasis._x000D_ Other Notes_x000D_ A sample Certificate of Analysis is available for this product._x000D_ Please type the word sample in the text box provided for lot number.