Description_x000D_ General description_x000D_ The antibody pair provided in this kit recognizes human Urokinase Plasminogen Activator Surface Receptor._x000D_ Application_x000D_ For research use only. Not for use in diagnostic procedures._x000D_ Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)_x000D_ Biochem/physiol Actions_x000D_ Plasminogen activator, urokinase receptor (PLAUR) is implicated in tumor invasion, angiogenesis and metastasis. It acts as a key regulator of cell-surface plasminogen activator. It is involved in various normal and pathological processes. Overexpression of the gene has been observed in various types of cancers, including head and neck squamous cell carcinoma (HNSCC). Thus, it is considered as an potent biomarker for targeted imaging or therapy. Elevated expression of PLAUR leads to the progression of kidney disease in children._x000D_ Other Notes_x000D_ A sample Certificate of Analysis is available for this product._x000D_ Please type the word sample in the text box provided for lot number.