Description_x000D_ General description_x000D_ Identity of IgG3, lambda light chain is verified by subclass monoclonal antibodies and type specific polyclonal antibodies in immunoelectrphoresis and indirect ELISA assays._x000D_ IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections. IgG3 is the has a unique extended hinge region conferring greater flexibility_x000D_ IgG3, λ from human myeloma plasma is purified by fractionation, ion-exchange and affinity chromatography._x000D_ Mammalian immunoglobins contain either lambda or kappa light chains._x000D_ Application_x000D_ IgG3, lambda light chain may be used as an antigen for the production and evaluation of antibodies developed for the indentification and classification of IgG3 subtypes. The purified IgG3, lambda may be used as an immunoglobulin calibrator, reference antigen, blocking agent or coating protein in a variety of immunoassays including ELISA, dot-blot immunobinding, Western immunoblotting, immunodiffusion, immunoelectrophoresis, hemagglutination, and cell-binding assays._x000D_ The purified IgG3, λ may be used as an immunoglobulin calibrator, reference antigen, blocking agent or coating protein in a variety of immunoassays including ELISA, dot-blot immunobinding, Western immunoblotting, immunodiffusion, immunoelectrophoresis, hemagglutination, and cell-binding assays._x000D_ Physical form_x000D_ Solution in 20 mM tris buffered saline, pH 8.0._x000D_ Analysis Note_x000D_ The purity and identity are determined by immunoelectrophoresis, indirect ELISA, and SDS-PAGE._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.