Description_x000D_ General description_x000D_ The insulin gene is mapped to human chromosome 11p15.5._x000D_ Application_x000D_ Insulin from bovine pancreas has been used in endometrium cell culture. It has also been used to perform insulin tolerance test and to study the effect of protein undernutrition in laying hens._x000D_ Insulin from bovine pancreas was used during experimental design and treatments. Experimental animals (like cow) were infused with bovine insulin to decrease blood glucose to a constant level._x000D_ Packaging_x000D_ 50, 100, 250, 500 mg in poly bottle_x000D_ Biochem/physiol Actions_x000D_ Abnormal insulin secretion or function leads to diabetes mellitus, obesity and other carbohydrate metabolism disorders. The biological effects of insulin are mediated by insulin receptor (glycoprotein) and it integrates major signaling pathways._x000D_ Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. Its molecular weight is ~5800 Da. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat._x000D_ Legal Information_x000D_ Hybri-Max is a trademark of Sigma-Aldrich Co. LLC