Description_x000D_ Packaging_x000D_ 1 g in poly bottle_x000D_ 500 mg in poly bottle_x000D_ Biochem/physiol Actions_x000D_ Isocitrate dehydrogenase (IDH) plays a major role in the Krebs cycle by catalyzing the oxidative decarboxylation of isocitrate. The oxidative decarboxylation of isocitrate generates α-ketoglutarate and NADPH. NADPH produced is essential for the production of fatty acids and cholesterol. This NADP-dependent molecules serves as homodimers._x000D_ Quality_x000D_ Crude_x000D_ Unit Definition_x000D_ One unit will convert 1.0 μmole of isocitrate to α-ketoglutarate per min at pH 7.4 at 37°C.