Description_x000D_ Biochem/physiol Actions_x000D_ KDR (kinase insert domain receptor) is a transmembrane tyrosine kinase receptor which interacts with VEGF (vascular endothelial growth factor) and helps in mediating VEGF downstream angiogenic effects. Blocking KDR suppresses tumor growth and abrogates tumor cell invasion._x000D_ Physical form_x000D_ Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol._x000D_ Legal Information_x000D_ PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC