Description_x000D_ General description_x000D_ Phosphatidylcholine belongs to the class of glycerophoshpolipids and contains choline as the head-group. Choline is attached to the glycerol of fatty acids ester-bound to backbone. It is the major phospholipid found in eukaryotic organism._x000D_ Application_x000D_ L-α-Phosphatidylcholine has been used:_x000D_ • to form a thin lipid film used in Kupffer cell depletion by liposome-encapsulated clodronate_x000D_ • as a component of assay buffer used in γ-secretase in vitro assay_x000D_ • in the preparation of substrate mix for its use in HPLC (high performance liquid chromatography) assay of 5-lipoxygenase enzyme activity_x000D_ Packaging_x000D_ 1 g in glass bottle_x000D_ 25, 100, 500 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ It also acts as a source of lipid messengers/ bioactive lipids including: lysophosphatidylcholine, diacylglycerol, phosphatidic acid, lysophosphatidylcholine, arachidonic acid and platelet activating factor. Phosphatidylcholine is produced in the liver by the CDP-choline (cytidine diphosphocholine) pathway._x000D_ A major structural phospholipid in brain, comprising approx. 15% of total lipid; primarily localized to gray matter._x000D_ Packaging_x000D_ Packaged under Argon_x000D_ Preparation Note_x000D_ Prepared by a modification of the procedure of Singleton, W.S., et al., J. Am. Oil Chem. Soc., 42, 53 (1965).