Description_x000D_ Application_x000D_ L-Arginine has been used:_x000D_ • as a Roswell park memorial institute medium (RPMI) media component in the isolation and culture of peripheral blood mononuclear cells (PBMCs)_x000D_ • as a RPMI media component for tissue culture_x000D_ • in DMEM medium for the identification and quantification of phosphorylation sites by stable isotope labeling by amino acids in cell culture (SILAC) and LCMS/MS_x000D_ Packaging_x000D_ 1 kg in poly bottle_x000D_ 10 mg in glass bottle_x000D_ 25, 100 g in poly bottle_x000D_ Biochem/physiol Actions_x000D_ L-Arginine is a conditionally essential amino acid, that play a vital role in the production of nitric oxide. It acts as a precursor for the synthesis of polyamines, agmatine and urea. L-Arginine is usually essential in children and non-essential in adults._x000D_ Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.