Description_x000D_ Application_x000D_ L-Citrulline has been used in ultra-performance liquid chromatography to validate, metabolites involved in the coordination of metamorphic processes._x000D_ Packaging_x000D_ 10 mg in autosample vial_x000D_ 5, 25 g in poly bottle_x000D_ Biochem/physiol Actions_x000D_ Intermediate in the production of nitric oxide from L-arginine by NO synthetase._x000D_ L-Citrulline, when orally administered is found to ameliorate the condition of sickle cell disease in humans. L-citrulline can be a replacement for L-arginine administration in case of defective NO synthetase. L-Citrulline supplementation is found to fulfill the purpose of NO-dependent signaling._x000D_ Other Notes_x000D_ Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C7629.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.