Description_x000D_ Packaging_x000D_ 10, 25, 100 mg in poly bottle_x000D_ 250 mg in poly tube_x000D_ Biochem/physiol Actions_x000D_ Blocks sphingosine biosynthesis by inhibition of ketosphinganine synthetase. Cytotoxicity toward neuroblastoma and medulloblastoma cells mediated by suppression of ganglioside synthesis._x000D_ L-cycloserine is a potent inhibitor of serine palmitoyltransferase, the first step of sphingolipid synthesis._x000D_ Features and Benefits_x000D_ This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more._x000D_ Legal Information_x000D_ LOPAC is a registered trademark of Sigma-Aldrich Co. LLC