Description_x000D_ Amino Acid Sequence_x000D_ γ-Glu-Cys-Gly_x000D_ Packaging_x000D_ 5, 10, 25, 100 g in poly bottle_x000D_ Application_x000D_ May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose._x000D_ Biochem/physiol Actions_x000D_ Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.