Description_x000D_ Amino Acid Sequence_x000D_ Arg-Arg-Trp-Gln-Trp-Arg-Met-Lys-Lys-Leu-Gly_x000D_ General description_x000D_ Chemical structure: peptide_x000D_ Application_x000D_ Lactoferricin B, fragment 4-14 trifluoroacetate salt has been used to study effect of lactoferricin on cell proliferation of human colon cancer cells. It has been used in study of ultraviolet light-mediated DNA damage in human colon cancer cells._x000D_ Biochem/physiol Actions_x000D_ Lactoferricin B also suppresses liver and lung metastasis in murine melanomas and lymphomas. In addition, it causes cell death in human leukemic and carcinoma cell lines. It is effective against Escherichia coli, Salmonella enteritidis, Klebsiella pneumoniae, Proteus vulgaris, Yersinia enterocolitica, Pseudomonas aeruginosa, Campylobacter jejuni, Staphylococcus aureus, Streptococcus mutans, Corynebacterium diphtheriae, Listeria monocytogenes and Clostridium perfringens._x000D_ Antibiotic peptide in colostrum and milk that protects from bacterial infection at mucosal surfaces.