Description_x000D_ Application_x000D_ Fluorescence microscopy, fluorescent retinoid binding assay, fluorescence spectroscopy._x000D_ Biochem/physiol Actions_x000D_ Strong ligand for retinoic acid receptor proteins_x000D_ Features and Benefits_x000D_ LightOx26 is a synthetic analogue of all-trans-retinoic acid (ATRA), that exhibits solvatochromatic fluorescence emission when excited with UV or 405 nm light. The compound is a strong ligand for the retinoic acid receptor proteins (RARs) and related cellular retinoic acid binding proteins (CRABPI/II) and can, therefore, be used as a replacement for ATRA in cellular assays involving retinoid signaling processes. LightOx26 can be utilised to study retinoid behaviour using fluorescence microscopy, employed in a competitive fluorometric ligand-binding assay for direct determination of the strength of binding of non-fluorescent retinoids to a protein target, and as a fluorophore in fluorescence spectroscopy._x000D_ Other Notes_x000D_ Chemical Equivalency 1ea=1mg_x000D_ Legal Information_x000D_ LightOx is a trademark of LightOx Ltd.