Description General description Methyl indole-5-carboxylate (Methyl 1H-indole-5-carboxylate), a substituted 1H-indole, can be prepared by the esterification of indole-5-carboxylic acid.[7] Its efficacy as a substrate for indigoid generation has been assessed.[3] Application Methyl indole-5-carboxylate may be used as a reactant in the following processes: • biosynthesis of inhibitors of protein kinases[3] • metal-free Friedel-Crafts alkylation[4] • preparation of diphenylsulfonium ylides from Martin′s sulfurane[2] • cross dehydrogenative coupling reactions[1] • synthesis of indirubin derivatives[5] • preparation of aminoindolylacetates[6] Methyl indole-5-carboxylate may be used in the preparation of: • methyl indoline-5-carboxylate[8] • 1H-indole-5-carbohydrazide[7] • dimethyl 1H-indole-3,5-dicarboxylate[9] Packaging 1, 5 g in glass bottle