Description_x000D_ General description_x000D_ The ready-to-use MISSION miRNA mimics are small, double-stranded RNA molecules designed to mimic endogenous mature miRNA molecules when introduced into cells. miRNA are known to regulate gene expression in a variety of manners, including translational repression, mRNA cleavage and deadenylation. MISSION miRNA Mimics, a member of MISSION RNAi product family, provides miRNA researchers with a range of options from individual MISSION mimics to a full library of human miRNA mimics based on latest version of miRBase (currently hosted by the University of Manchester, previously hosted by the Sanger Institute)._x000D_ • Optimized and ready for transfection.Novel MISSION miRNA mimic design has been functionally tested for knockdown efficiency against natural miRNA targets.Unique MISSION miRNA mimic design significantly reduces possible sense strand off target effects._x000D_ • Available as a whole human library and individual miRNA targets._x000D_ Legal Information_x000D_ MISSION is a registered trademark of Sigma-Aldrich Co. LLC