Description_x000D_ General description_x000D_ ASNA1 is the human homolog of the bacterial arsA gene. In E. coli, ArsA ATPase is the catalytic component of a multisubunit oxyanion pump that is responsible for resistance to arsenicals and antimonials._x000D_ TMD recognition complex of 40 kDa (TRC40) also known as arsA arsenite transporter, ATP-binding, homolog 1 (ASNA1), is encoded by the gene mapped to human chromosome 19p13.2. ASNA1 is the mammalian ortholog of yeast Arr4/Get3 gene. The encoded protein is abundantly expressed in pancreatic β cells._x000D_ Immunogen_x000D_ ASNA1 (NP_004308, 239 a.a. ~ 348 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa._x000D_ Sequence_x000D_ PEQTTFICVCIAEFLSLYETERLIQELAKCKIDTHNIIVNQLVFPDPEKPCKMCEARHKIQAKYLDQMEDLYEDFHIVKLPLLPHEVRGADKVNTFSALLLEPYKPPSAQ_x000D_ Physical form_x000D_ Solution in phosphate buffered saline, pH 7.4_x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Legal Information_x000D_ GenBank is a registered trademark of United States Department of Health and Human Services_x000D_ Biochem/physiol Actions_x000D_ Asna1/TRC40 interacts with the transmembrane domains (TMD) of newly released tail-anchored (TA) proteins and transfers them to the endoplasmic reticulum (ER) receptor for subsequent membrane insertion and thus, plays an essential role in TA protein biogenesis. The encoded protein is necessary for effective HSV1 replication. Asna1 acts as a key regulator of insulin signaling in C. elegans and mammalian cells._x000D_ Features and Benefits_x000D_ Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.