Description_x000D_ General description_x000D_ Chondroitin sulfate proteoglycan 6 (CSPG6) or structural maintenance of chromosomes 3 (SMC3) is a member of the cohesin complex. The gene encoding this protein is localized on human chromosome 10q25.2._x000D_ Immunogen_x000D_ CSPG6 (AAH47324, 711 a.a. ~ 810 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa._x000D_ Sequence_x000D_ IDQLMNQMQQIETQQRKFKASRDSILSEMKMLKEKRQQSEKTFMPKQRSLQSLEASLHAMESTRESLKAELGTDLLSQLSLEDQKRVDALNDEIRQLQQE_x000D_ Physical form_x000D_ Solution in phosphate buffered saline, pH 7.4_x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ Chondroitin sulfate proteoglycan 6 (CSPG6) or structural maintenance of chromosomes 3 (SMC3) assists in sister chromatid separation and microtubule-mediated intracellular transport. It is also involved in DNA repair and recombination. The protein has been associated with colon carcinoma.