Description_x000D_ General description_x000D_ Cytokeratins also known as keratins are filament-forming proteins of epithelial cells. In humans, there are 54 cytokeratins. These proteins are divided in to two sub-categories such as acidic type I keratins and basic-to-neutral type II keratins._x000D_ The antibody C-11 reacts with Cytokeratin peptides 4, 5, 6, 8, 10, 13, 18. Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues._x000D_ Immunogen_x000D_ Keratin-enriched preparation from human epidermoid carcinoma cell line A431_x000D_ Application_x000D_ Monoclonal Anti-Cytokeratin (Pan-reactive) antibody produced in mouse has been used in immunocytochemistry._x000D_ The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 0.5 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator._x000D_ Physical form_x000D_ Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ Cytokeratins play an essential role in normal tissue structure and function. It also facilitates the maintenance of cell mechanical integrity._x000D_ Features and Benefits_x000D_ Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.