Description_x000D_ General description_x000D_ Deoxyuridine triphosphate nucleotidohydrolase (dUTPase) maintains the genomic integrity of cells. This enzyme is a symmetrical trimer with 152 amino acids._x000D_ Immunogen_x000D_ human dUTPase protein._x000D_ Physical form_x000D_ Solution in 0.01M phosphate buffered saline pH 7.4, containing 15 mM sodium azide._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ Deoxyuridine triphosphate nucleotidohydrolase (dUTPase) hydrolyses dUTP to dUMP and pyrophosphate and promotes nucleotide metabolism. Epstein-Barr virus (EBV) encoded dUTP plays a crucial role in pathophysiology of EBV related diseases, by regulating cellular microenvironment. It is used as a target for anticancer chemotherapy.