Description_x000D_ General description_x000D_ Glutamic Acid Decarboxylase 67 (GAD67) is encoded by the gene glutamic acid decarboxylase 1 (GAD1). GAD1 gene is located on the human chromosome at 2q31.1. GAD67 is localized in the dendrites and cell bodies._x000D_ Specificity_x000D_ Reacts specifically with GAD67. Does not crossreact with GAD65._x000D_ Immunogen_x000D_ This peptide does not share homology with GAD65._x000D_ synthetic peptide from mouse GAD67 (amino acids 87-106)._x000D_ Application_x000D_ Monoclonal anti-glutamic acid decarboxylase 67 (GAD67) antibody produced in mouse has been used in:_x000D_ • immunohistofluorescence_x000D_ • western blotting_x000D_ • immunohistochemistry._x000D_ Physical form_x000D_ Solution in phosphate buffered saline containing 0.01% sodium azide._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ Glutamic Acid Decarboxylase 67 (GAD67) is involved in the production of γ-amino butyric acid (GABA), a inhibitory neurotransmitter in the central nervous system (CNS). Deficiency of GAD67 leads to psychosis, schizophrenia and bipolar diseases.