Description_x000D_ General description_x000D_ IgG is the main type of antibody in human serum, secreted by the B cells. It is found in blood. IgG consists of four polypeptide chains, made of two identical 50 kDa γ heavy (H) chains and two identical 25 kDa κ or λ light (L) chains, which are linked by inter-chain disulfide bonds. IgG contains four isotypes IgG1, IgG2, IgG3 and IgG4._x000D_ The antibody reacts with an epitope located on the heavy chain of goat IgG1 and IgG2._x000D_ Application_x000D_ Monoclonal Anti-Goat/Sheep IgG antibody produced in mouse has been used in:_x000D_ • enzyme linked immunosorbent assay (ELISA)_x000D_ • immunoblot_x000D_ • immunoprecipitation_x000D_ • immunoelectrophoresis_x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ IgG stimulates the classical pathway of the complement system. It neutralizes virus particles and toxins. IgG plays a crucial role in antibody-dependent cell-mediated cytotoxicity (ADCC). IgG might be associated with allergy. It has the longest serum half life.