Description_x000D_ General description_x000D_ HRas proto-oncogene, guanosine triphosphatase (GTPase) (HRAS) belongs to the family of Ras proteins and is mapped to human chromosome 11p15.5._x000D_ Immunogen_x000D_ HRAS purified recombinant protein_x000D_ Physical form_x000D_ Solution in Dulbecco′s Modified Eagle′s Medium with 10% fetal calf serum and 15 mM sodium azide._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ Mutation in HRas proto-oncogene, guanosine triphosphatase (GTPase) (HRAS) gene is widely observed in many cancer types. Heterozygous germline variation in this gene causes Costello syndrome, which is a severe developmental disorder.