Description_x000D_ General description_x000D_ Indoleamine 2,3-dioxygenase 2 (IDO2) gene is mapped to human chromosome 8p11.2. The gene is expressed in the brain, liver, kidney, placenta and the epididymis of mice._x000D_ Immunogen_x000D_ IDO2 purified recombinant protein_x000D_ Physical form_x000D_ Solution in Dulbecco′s Modified Eagle′s Medium with 10% fetal calf serum and 15 mM sodium azide._x000D_ Biochem/physiol Actions_x000D_ Indoleamine 2,3-dioxygenase 2 (IDO2) has dioxygenation action on l-tryptophan to synthesis kynurenine. IDO2 has immune modulatory function. In the condition of multiple tumor, it represses the action of immune system. IDO2 is implicated in B cell-mediated autoimmune diseases, gastric, colon and pancreatic cancer cell tumors.