Description_x000D_ General description_x000D_ Interleukin 2 (IL2) is synthesised by immunoregulatory T helper cells. IL2 consists of three subunits, in which the beta subunit is critical for receptor mediated signalling. IL2 gene is located on human chromosome 4q27._x000D_ Immunogen_x000D_ IL2 (NP_000577, 21 a.a. ~ 153 a.a) recombinant protein._x000D_ Sequence_x000D_ MAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFSQSIISTLT_x000D_ Physical form_x000D_ Solution in phosphate buffered saline, pH 7.4_x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Legal Information_x000D_ GenBank is a registered trademark of United States Department of Health and Human Services_x000D_ Biochem/physiol Actions_x000D_ Interleukin 2 (IL2) promotes the development of suppressor T regulatory cells. IL2 plays a crucial role in antitumor immunity. IL2 destabilises adherens junctions, and cytoskeletal reorganization, causing increased endothelial cell permeability.