Description_x000D_ General description_x000D_ Potassium voltage-gated channel subfamily B member 1 (KCNB1) is widely distributed in the central nervous system. The gene ID for the protein is 25736._x000D_ Specificity_x000D_ Detects ~105-125 kDa (varies with cell background due to phosphorylation). No crossreactivity to rat Kv2.2._x000D_ Immunogen_x000D_ Synthetic peptide amino acids 837-853 (cytoplamsic Cterminus) of rat KV2.1(HMLPGGGAHGSTRDQSI),Accession Number NP_037318._x000D_ Physical form_x000D_ Solution in PBS, pH 7.4, 50% glycerol, and 0.09% sodium azide_x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ Potassium voltage-gated channel subfamily B member 1 (KCNB1) forms microdomains to aid in protein trafficking and has a role in smooth muscle contraction. KCNB1 also takes part in membrane fusion activities. Studies on Chinese hamster ovary (CHO) cells have shown that this protein has a role in apoptosis._x000D_ Features and Benefits_x000D_ Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.